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PROTACs

PRL has also supporting chemical biology projects to deliver bespoke, high-quality tools such as PROTAC, DUBTAC and Degraded Antibody Conjugation projects and associated tools and Click chemistry tools to positively impact target validation and mechanistic understanding that includes cutting-edge research to prepares key diverse intermediates alongside developing optimised construction methods to prepare these complex molecules in the most efficient manner.

PROTACs, Molecular glue synthesis, Linker optimisation using various length and match-pair (PEG/Alkyl/Rigid linkers) as per client requirements with Thalidomide, VHL, Lenalidomide, Pomalidomide in high purity and adequate to allow clients for rapid screening for ADME and in vitro biological activity.

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